CBD is finding its name discussed frequently across beauty and wellness markets; however, its precursor molecule, CBDA (Cannabidiolic Acid), does not get the same interest.
CBDA is found most commonly in raw industrial hemp plants. A lot of extraction procedures extract CBDA initially before decarboxylating it to produce the active CBD molecule. Decarboxylation is the activation process that happens over time, exposing molecules to heat or sunlight, and air, transforming CBDA into the more widely known CBD.
CBD vs CBDA: What’s the difference?
Although they are closely related, CBD and CBDA are two different compounds. Structurally, the CBDA particle contains the extra COOH group, which decarboxylation extracts, transforming the molecule to CBD. While CBD is recognized to connect with the CB2 molecules, CBDA interacts with the endocannabinoid system by preventing the cyclooxygenase-2 (COX-2) enzyme. This difference in interaction results in unique benefits between the two molecules.
What are the potential health benefits of CBDA?
A lot of cannabinoid study is focused on CBD. Nevertheless, the handful of studies concentrating on CBDA show the particle’s potential to outmatch CBD in some circumstances. While more research still requires to be done, the main research on CBDA exposed interesting feasible applications potential, consisting of:
- Inhibiting irregular cell growth
- Epilepsy therapy
- Anti-inflammatory
- Anti-nausea
- Anti-depressant
The key study suggests that CBDA has better bioavailability than CBD, allowing the body to metabolize the substance quicker and with less initiative. Scientists have revealed that CBDA has 100 times the affinity for the 5-HT receptors compared to CBD. For these reasons, it is hypothesized that CBDA can have more effective effects than CBD.
Formulating with CBDA
When it comes to creating solutions with CBDA, it prevails to include other cannabinoids. Preferably, cosmetics formulas combine CBDA isolates with various other isolate cannabinoids, such as CBD and CBG, to produce reliable formulations. A strong understanding of each component is important to producing mixes that work.
How to use CBDA?
CBDA isolate is suitable for ingestible products such as CBDA tinctures, gummies, and softgels. CBDA raw ingredients are meant for formulating right into finished CBDA products. When formulating with acidic cannabinoids, do not let the product’s temperature boost over 70 ° C for more than 30 minutes to avoid decarboxylation.
How to store CBDA?
Keep the container tightly closed in a dry and well-ventilated place. Recommended storage space temperature: 2 – 8 ° C. Avoid direct exposure to light, high temperature, and wetness.
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